In order to characterize the effect of compounds, biological analyses give precious information on the release of the compound and on direct or indirect effect thanks to blood or urine analysis. Samples are collected during the study (specific time points to be decided in the study plan) and/or at the end of the study before necropsy if relevant.
Samples can also be delivered by the Sponsor for specific analyses and Atlantic Bone Screen will advice for the sampling, storage and transport conditions in order to get samples the best way and be sure providing robust data.
Statistical analysis are also applied according to the analysis, the number of samples, the number of animals/patients… etc
Research Services
Our services aims at supporting early research programs of our customers with validated and innovative models and solutions. Thanks to our specific expertise and our flexibility, our Team do provide robust and reliable advice and results to accelerate drug development. Our drug discovery services can especially include both consultant services, complete studies implementation or technical services: explore our wide range of non regulatory preclinical models and expertise:
- In Vitro Pharmacology – Lab-based studies on compound behavior on cells differencitation or cells activity
- In Vivo Pharmacology – Test on rodent (in house) or big animals (with a local Partner)Toxicology and Safety Assessment – Evaluation of safety profiles
- Ex vivo services – Either included into a global study on on samples we receive from your labs or from other platforms, we can proceed histology, biomarkers analyses, image analyses…
Here below are some axamples of studies we can perform to support your drug candidate preclinical and biomaterials development:
- Toxicology and Safety Assessment – Evaluation of safety profilesPharmacokinetics (PK) and Pharmacodynamics (PD) – Assess drug / biomaterial behavior
- Toxicology Services – Comprehensive property non regulatory studies
- Biomarker analyses – Identify and dose spcific markers
- Target Identification and Validation – Confirm the relevance of molecular targets in pilot studies
- Lead Optimization – Refine lead candidates or compare different formulations
- Formulation Development – Enhance drug delivery and optimize formulations
- DMPK (Drug Metabolism and Pharmacokinetics) Services – Understand drug metabolism
A broad range of preclinical services & models
Taking into account your requirements, goals and timelines, Atlantic Bone Screen puts all its efforts to support you in the choice of the right model and evaluate the behaviour of your drug candidate, nutraceutical or biomaterial once adminstrated or implanted in rodents or bigger animals (rabbit, sheep…).
Atlantic Bone Screen can provide various models and study design to answer your needs and consolidate your preclinical data for further regulatory tests, in high quality standards and expertise.
Thanks to our own rodent animal facility, we can also house your animals always keeping in mind the 3R’s rules and welfare of the animals.
From sampling to histopathological analyses, our team daily provides histological processing of any kind of samples for histomorphometry and histopathology analyses.
Entrust us with your samples, either for only technical histological process, for one or several steps, or for the whole process with histomorphometry and histopathology analyses.
A large range of histology services are available in the field of inflammation, in oncology, in dermatology, in neurology…
Whether you require 3D analysis of bone architecture, high-resolution cellular imaging, or quantitative histological evaluations, our services are tailored to deliver reliable and actionable results.
To answer our Customers’ needs, Atlantic Bone Screen has developed a platform for image analyses with different techniques, microscopes and software. Our cutting-edge imaging capabilities provide detailed and quantitative insights into biological structures and processes. Combining state-of-the-art technologies with expert analysis, we support a wide range of preclinical studies with high-resolution data tailored to your research needs.
In order to characterize the effect of compounds, biological analyses give precious information on the release of the compound and on direct or indirect effect thanks to blood or urine analysis. Samples are collected during the study (specific time points to be decided in the study plan) and/or at the end of the study before necropsy if relevant.
Samples can also be delivered by the Sponsor for specific analyses and Atlantic Bone Screen will advice for the sampling, storage and transport conditions in order to get samples the best way and be sure providing robust data.
Statistical analysis are also applied according to the analysis, the number of samples, the number of animals/patients…etc
Pathological models mimicking human and animal pathologies such as osteoporosis, osteoarthritis, rheumatoid arthritis...
Robust models on tumoral cell lines and in vivo oncological models to validate future drugs for bone cancer, bone metastases and more globally solid tumors
Validated assays for in vitro cytotoxicity and in vivo biocompatibility evaluation in regenerative medicine; also animal implantation models to validate efficacy of biomaterials
In vitro and ex vivo models applied to dermocosmetics products to better understand mechanism of actions of compounds and products efficacy
Preclinical models applied to inflammatory diseases to better understand mechanism of actions of compounds and treatment efficacy
Optimize and accelerate the development of your compounds. High-Quality expertise in the field of bone and joint diseases,
Histological and imagery services as an endpoint for in vivo analysis Ex-vivo analysis of your own samples Download
Applications for Health Care, Food and Cosmetic Industries : Drug candidates, Nutraceutials, Biomaterials, Formulations and more. Primary cells
Identification and characterization of the therapeutic effect of your compounds. Applications for Health Care, Food and Cosmetic Industries