X-ray 2D Radiography is a rapid, non-invasive imaging modality offering high-resolution visualization of skeletal structures and soft tissue contrats. In preclinical studies, it is widely used to assess bone integrity, fracture repair and tumor progression either :

• In vivo, enabling real-time monitoring thourghout the course of the study with minimal stress to the animal or,
• Ex vivo, allowing detailed analysis of harvested samples at endpoint providing complementary structural information.

These approaches support longitudinal evaluation with minimal animal handling, making them highly effective for tracking disease progression and therapeutic outcomes while improving study efficiency and translational relevance.

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