Preclinical models for inflammation research

Our comprehensive range of preclinical models offers precise and reliable solutions for studying inflammation across various biological systems. These platforms support the development of anti-inflammatory therapies through detailed mechanistic insights and biomarker analysis.

With deep expertise in inflammation research, we tailor our models to bridge the gap between early discovery and clinical applications. Whether your focus is on immune-mediated diseases, arthritis, or inflammation-related conditions, our models provide robust insights and reliable data to advance your projects…

In Vitro Models: Macrophages

We provide in vitro inflammation models based on primary macrophages at different polarization stages (M0, M1). These models are ideal for:

• Investigating pro-inflammatory pathways and cytokine release.
• Evaluating the efficacy of anti-inflammatory compounds.
• Exploring macrophage-mediated immune responses.

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In Vivo Models: Joint Inflammation

Our expertise includes animal models of arthritis, mimicking joint inflammation and damage as seen in human inflammatory diseases. These models enable:

• Efficacy testing of anti-inflammatory and disease-modifying agents.
• Biomarker profiling for translational studies.
• Longitudinal assessment of therapeutic interventions in chronic inflammation.

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Biomarkers Quantification

We offer advanced assays for measuring key inflammatory biomarkers, such as:

• Interleukins (e.g., IL-1β, IL-6, IL-10).
• Tumor Necrosis Factor-alpha (TNF-α) and other cytokines

Our biomarker services provide quantitative and reproducible data for preclinical studies, supporting the identification of therapeutic targets and validation of drug efficacy.

Histological Expertise

Our histopathology services utilize cutting-edge techniques to evaluate inflammation in all tissue types:

• Hematoxylin-Eosin (HE) and Hematoxylin-Eosin-Safran (HES) staining for tissue architecture and inflammatory cell infiltration.
• Immunohistochemistry with specific markers to detect and quantify inflammatory mediators at the tissue level.

Discover our research services